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2 4-Dichloro-5-methylpyrimidineCAS# 1780-31-0) Image Featured
  • 2 4-Dichloro-5-methylpyrimidineCAS# 1780-31-0) 1

2 4-Dichloro-5-methylpyrimidineCAS# 1780-31-0)

Chemical Property:

Formulae hypotheticae C5H4Cl2N2
Molar Mass 163
Densitas 1.39 g/mL ad 25 °C (lit.)
Liquefactio Point 26-28 °C.
Boling Point 108-109 °F .
Flash Point >230°F
Solubilitas Solutum in chloroformi, aethere, ethylo, acetate et toluene
Vapor Pressura 0.093mmHg ad 25°C
Aspectus pulveris ut massa patet liquido
Color Alba vel hyalina vel fere alba vel fere hyalina
pKa -2.44±0.29 (Praedicta)
Repono Condition Inertia atmosphaera, 2-8 ° C *

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Product Tags

Periculum et salus

Periculum symbola C - Corrosive
Periculum Codes XXXIV - Causa urit
Salus Descriptio S26 - In contactu cum oculis, statim cum aqua multa ablue et consilium quaere medicinae.
S36/37/39 - Vestis tutelae, chirothecae et oculi/faciei tutelam idoneam induere.
S45 - In casu accidentis vel si bene sentis, consilium medicinae statim quaere (litteras cum fieri potest demonstrare).
S27 — Statim omnem contaminatam vestem exue.
Consociatione Nationum IDs UN 3261 8/PG 2
WGK Germania 3
TSCA Ita
HS Code* 29335990
Periculum Classis 8
Stipare Group III

2 4-Dichloro-5-methylpyrimidineCAS# 1780-31-0) Information

Usus 2, 4-dichloro-5-methylpyrimidine adhiberi potest in praeparatione 2-fluoro-5-trifluoromethylpyrimidine. 2-fluoro-5-trifluoromethylpyrimidine media est momenti pro synthesi pharmaceuticarum, quae adhiberi potest ad synthesim anuli dihydrofurani compositorum fusorum, et anulus mixtorum dihydrofuranorum fusorum uti potest sicut receptor GPR119 modulatorum G interdum copulatorum, pro diabete tractando; dolore magna aliqua et dyslipidemia morbo. Praeter, 2-fluoro-5-trifluoromethylpyrimidines adhiberi potest etiam ut media in synthesi medicamentorum ad curationem morborum Alzheimer et schizophreniae.
praeparatio 5-methyluracil 75g(0.59mol), phosphorus oxychloridum 236g, triethylamina hydrochloridum 16.5g(0.12mol), addita reactioni lagona, calefacta ad 100 ~ 110 , reactionem 5H, refrigeratum ad 40 , phosphorum pentachloridum 248 (adde. 1.19mol), calor conservationis reactio 2H. Post peractam reactionem, phosphorus oxychloridum per distillationem sub pressura reducta recuperatum est, et distillatio sub pressione reducta continuata est ad obtinendum 88g(0.54mol) de 2, 4-dichloro-5-methylpyrimidine in cedente 91.5%.
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