5-Fluorouracil（CAS# 51-21-8)

Chemical Property:

Formulae hypotheticae	C4H3FN2O2
Molar Mass	130.08
Densitas	1.4593 (aestima)
Liquefactio Point	282-286 °C (decl.)
Boling Point	190-200°C/0.1mmHg
Aqua Solubility	12.2 g/L 20 C
Solubilitas	Leviter solutum in ethanol. Prope insolubile est in solutione chloroformi et in sodium hydroxide resolutum.
Aspectus	Album aut album-sicut crystallinum pulveris
Color	album
Merck	14,4181
BRN	127172
pKa	pKa 8.0±0.1 (H2O) (incerta); 3.0±0.1(H2O)
PH	4.3-5.3 (10g/l, H2O, 20℃)
Repono Condition	2-8°C
Stabilitas	Stabulum. Lux sensibilis. Combustible. Compatible cum validis oxidizing agentium, bases fortes.
Sensitiva	Air Sensitiva
Index refractivus	1.542
MDL	MCD00006018
Physica et Chemical Properties	punctum liquefaciens 282-286°C (decl.) solubility H2O: 10 mg/mL, clarum forma pulveris color albus aqua solubility 12.2g/L 20 c Sensitiva Air merck 14,4181 BRN 127172
Usus	Cancer ad systema digestivum, cancer capitis et colli, cancer gynecologicus, cancer pulmonis, cancer jecoris, cancer vesicae et curatio cancer cutis

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Product Detail

Product Tags

Periculum Codes	R22 - noxium absorptus R20/21/22 - Inspiratio noxia, in contactu cum cute et absorpta. R52 - Noxia organismi aquatilium R25 - Toxicus absorptus
Salus Descriptio	S36 - Apta indumenta tutela gere. S36/37 - indumentis tutelae idoneis gere et caestus. S36/37/39 - Vestis tutelae, chirothecae et oculi/faciei tutelam idoneam induere. S22 — Pulverem noli spirare. S45 - In casu accidentis vel si bene sentis, consilium medicinae statim quaere (litteras cum fieri potest demonstrare). S26 - In contactu cum oculis, statim cum aqua multa ablue et consilium quaere medicinae.
Consociatione Nationum IDs	UN 2811 6.1/PG 3
WGK Germania	3
RTECS	YR0350000
FLUKA BRAND F CODES	10-23
TSCA	T
HS Code*	29335995
Aleam Nota	Irritant / Highly Toxicus
Periculum Classis	6.1
Stipare Group	III
Toxicity	LD50 viva voce in Rabbit: 230 mg/kg

Introductio

Hoc productum primum in nucleotides 5-fluoro-2-deoxyuracillorum convertitur in corpore, quod synthasin thyminum nucleotidis vetat et conversionem deoxyuracillorum nucleotidum in deoxythyminum nucleotides impedit, ita inhibens DNA biosynthesin. Praeterea, impediendo incorporationem acidi uracil et rotici in RNA, effectus inhibendi synthesin RNA obtinetur. Hoc productum est cyclum cella specifica medicamento, maxime inhibuit cellas S phase.

Priora: 2 6-Dichlorophenylhydrazinae hydrochloridi-CAS# 50709-36-9)

Next: 2-HYDROXY-3-AMINO-5-PICOLINE（CAS# 52334-51-7)

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