Methoxymethyl triphenylphosphonium chlorideCAS# 4009-98-7)

usus

(Methoxymethyl) triphenylphosphorus chloride adhibetur ad synthesinandam cefaltacin, quae est medicamento antivirali et anti-tumore. Usurpatur etiam fragmentum paclitaxel componi.

Praeparatio

Methodus synthesisandi (methoxymethyl) triphenylphosphori chloridi, sequentes gradus complectens: sub tutela nitrogenii, addita 50mL aceti anhydrosi in reactoris, deinde 32g triphenylphosphini addens, temperatura ad 37°C excitando et levando, temperaturam constantem servans. addens 20g yl chloromethyl aetheris reactori, et reagit ad XXXVII ° C pro 3h, temperatura lente elevando ad 47°C ad rate of 1°C/min, continuata est reactio pro 3h, omissus est motus, et 37.0g (methoxymethyl) triphenylphosphorus chloride consecutus est a filtratione, aethere anhydrico lavacro et exsiccatione. cum cedat 88.5%.